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VGF rabbit pAb

CAT: 0855-ES4026-02Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0855-ES4026-02Size:100 µL
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Background
This gene is specifically expressed in a subpopulation of neuroendocrine cells, and is upregulated by nerve growth factor. The structural organization of this gene is similar to that of the rat gene, and both the translated and the untranslated regions show a high degree of sequence similarity to the rat gene. The encoded secretory protein also shares similarities with the secretogranin/chromogranin family, however, its exact function is not known. [provided by RefSeq, Jul 2008]
Description
This gene is specifically expressed in a subpopulation of neuroendocrine cells, and is upregulated by nerve growth factor. The structural organization of this gene is similar to that of the rat gene, and both the translated and the untranslated regions show a high degree of sequence similarity to the rat gene. The encoded secretory protein also shares similarities with the secretogranin/chromogranin family, however, its exact function is not known. [provided by RefSeq, Jul 2008],
Product Name Alternative
VGF; Neurosecretory protein VGF
UniProt
O15240
Swiss Prot
O15240
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from the Internal region of human VGF. AA range:451-500
Target
VGF
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. IHC-p: 1/100-1/300. ELISA: 1/20000. Not yet tested in other applications.
Buffer
-20°C/1 year
Molecular Weight
67kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
67kD
Fragment
IgG
Subcellular Location
[Neurosecretory protein VGF]: Secreted . Cytoplasmic vesicle, secretory vesicle . Stored in secretory vesicles and then secreted, NERP peptides colocalize with vasopressin in the storage granules of hypothalamus.
Other Product Names
VGF; Neurosecretory protein VGF
Gene ID (Human)
7425

UniProtKB · O15240

Neurosecretory protein VGF

VGF_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
O15240
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
VGF
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
Q9UDW8
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

AmidationCleavage on pair of basic residuesPhosphoproteinPyrrolidone carboxylic acid

Molecular function

AntibioticAntimicrobialGrowth factor

Cellular component

Cytoplasmic vesicleSecreted

Domain

Signal

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