CDCP1 rabbit pAb

• Background:

  This gene encodes a transmembrane protein which contains three extracellular CUB domains and acts as a substrate for Src family kinases. The protein plays a role in the tyrosine phosphorylation-dependent regulation of cellular events that are involved in tumor invasion and metastasis. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, May 2013]

• Description:

  This gene encodes a transmembrane protein which contains three extracellular CUB domains and acts as a substrate for Src family kinases. The protein plays a role in the tyrosine phosphorylation-dependent regulation of cellular events that are involved in tumor invasion and metastasis. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, May 2013],

• UniProt:

  Q9H5V8

• Swiss Prot:

  Q9H5V8

• Reactivity:

  Human; Mouse; Rat

• Immunogen:

  The antiserum was produced against synthesized peptide derived from the Internal region of human CDCP1. AA range:241-290

• Clonality:

  Polyclonal

• Source:

  Rabbit

• Applications:

  WB; IHC; IF; ELISA

• Concentration:

  1 mg/ml

• Dilution:

  Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. Not yet tested in other applications.

• Molecular Weight:

  95kD

• Storage Conditions:

  -20°C/1 year

• Observed Molecular Weight:

  95kD

• Fragment:

  IgG

• Subcellular Location:

  [Isoform 1]: Cell membrane ; Single-pass membrane protein . Shedding may also lead to a soluble peptide.; [Isoform 3]: Secreted.

• Other Product Names:

  CDCP1; TRASK; CUB domain-containing protein 1; Membrane glycoprotein gp140; Subtractive immunization M plus HEp3-associated 135 kDa protein; SIMA135; Transmembrane and associated with src kinases; CD318

• Gene ID (Human):

  64866