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Kallistatin rabbit pAb

CAT: 0855-ES3946-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES3946-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Function:Inhibits human amidolytic and kininogenase activities of tissue kallikrein. Inhibition is achieved by formation of an equimolar, heat- and SDS-stable complex between the inhibitor and the enzyme, and generation of a small C-terminal fragment of the inhibitor due to cleavage at the reactive site by tissue kallikrein., miscellaneous:Heparin blocks kallistatin's complex formation with tissue kallikrein and abolishes its inhibitory effect on tissue kallikrein's activity., PTM:The N-terminus is blocked., similarity:Belongs to the serpin family., subunit:Monomer and some homodimers., tissue specificity:Expressed by the liver and secreted in plasma.
Description
Function: Inhibits human amidolytic and kininogenase activities of tissue kallikrein. Inhibition is achieved by formation of an equimolar, heat- and SDS-stable complex between the inhibitor and the enzyme, and generation of a small C-terminal fragment of the inhibitor due to cleavage at the reactive site by tissue kallikrein. miscellaneous: Heparin blocks kallistatin's complex formation with tissue kallikrein and abolishes its inhibitory effect on tissue kallikrein's activity. PTM: The N-terminus is blocked. similarity: Belongs to the serpin family. subunit: Monomer and some homodimers. tissue specificity: Expressed by the liver and secreted in plasma.
Product Name Alternative
SERPINA4; KST; PI4; Kallistatin; Kallikrein inhibitor; Peptidase inhibitor 4; PI-4; Serpin A4
UniProt
P29622
Swiss Prot
P29622
Reactivity
Human; Rat; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from the Internal region of human SERPINA4. AA range:161-210
Target
Kallistatin
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. Not yet tested in other applications.
Buffer
-20°C/1 year
Molecular Weight
47kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
47kD
Fragment
IgG
Subcellular Location
Secreted.
Other Product Names
SERPINA4; KST; PI4; Kallistatin; Kallikrein inhibitor; Peptidase inhibitor 4; PI-4; Serpin A4
Gene ID (Human)
5267

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