SV2C rabbit pAb

CAT: 0855-ES3807-01Size: 50 µLDry Ice: NoHazardous: No
CAT#:0855-ES3807-01Size:50 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Function:Plays a role in the control of regulated secretion in neural and endocrine cells, enhancing selectively low-frequency neurotransmission. Positively regulates vesicle fusion by maintaining the readily releasable pool of secretory vesicles., PTM:N-glycosylated., similarity:Belongs to the major facilitator superfamily., subcellular location:Enriched in small synaptic vesicles and adrenal microsomes, not present in chromaffin granules. Associated with both insulin granules and synaptic-like microvesicles in insulin-secreting cells of the pancreas., subunit:Interacts with SYT1 in a calcium-dependent manner.
Description
Function: Plays a role in the control of regulated secretion in neural and endocrine cells, enhancing selectively low-frequency neurotransmission. Positively regulates vesicle fusion by maintaining the readily releasable pool of secretory vesicles. PTM: N-glycosylated. similarity: Belongs to the major facilitator superfamily. subcellular location: Enriched in small synaptic vesicles and adrenal microsomes, not present in chromaffin granules. Associated with both insulin granules and synaptic-like microvesicles in insulin-secreting cells of the pancreas. subunit: Interacts with SYT1 in a calcium-dependent manner.
UniProt
Q496J9
Swiss Prot
Q496J9
Reactivity
Human; Mouse; Rat
Immunogen
Synthesized peptide derived from the Internal region of human SV2C.
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. Not yet tested in other applications.
Molecular Weight
82kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
82kD
Fragment
IgG
Subcellular Location
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane ; Multi-pass membrane protein . Enriched in small synaptic vesicles and adrenal microsomes, not present in chromaffin granules. Associated with both insulin granules and synaptic-like microvesicles in insulin-secreting cells of the pancreas. .
Other Product Names
SV2C; KIAA1054; Synaptic vesicle glycoprotein 2C
Gene ID (Human)
22987

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