Elmo1 rabbit pAb

CAT: 0855-ES3760-01Size: 50 µLDry Ice: NoHazardous: No
CAT#:0855-ES3760-01Size:50 µL
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Background
This gene encodes a member of the engulfment and cell motility protein family. These proteins interact with dedicator of cytokinesis proteins to promote phagocytosis and cell migration. Increased expression of this gene and dedicator of cytokinesis 1 may promote glioma cell invasion, and single nucleotide polymorphisms in this gene may be associated with diabetic nephropathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
Description
This gene encodes a member of the engulfment and cell motility protein family. These proteins interact with dedicator of cytokinesis proteins to promote phagocytosis and cell migration. Increased expression of this gene and dedicator of cytokinesis 1 may promote glioma cell invasion, and single nucleotide polymorphisms in this gene may be associated with diabetic nephropathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013],
Product Name Alternative
ELMO1; KIAA0281; Engulfment and cell motility protein 1; Protein ced-12 homolog
UniProt
Q92556
Swiss Prot
Q92556
Reactivity
Human; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human Elmo1. AA range:22-71
Target
Elmo1
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Buffer
-20°C/1 year
Molecular Weight
83kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
83kD
Fragment
IgG
Subcellular Location
Cytoplasm. Cell membrane. Translocation to plasma membrane seems to be mediated by DOCK1 and CRK.
Other Product Names
ELMO1; KIAA0281; Engulfment and cell motility protein 1; Protein ced-12 homolog
Gene ID (Human)
9844

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