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ZIP7 rabbit pAb

CAT: 0855-ES3730-02Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0855-ES3730-02Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene transports zinc from the Golgi and endoplasmic reticulum to the cytoplasm. This transport may be important for activation of tyrosine kinases, some of which could be involved in cancer progression. Therefore, modulation of the encoded protein could be useful as a therapeutic agent against cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
Description
The protein encoded by this gene transports zinc from the Golgi and endoplasmic reticulum to the cytoplasm. This transport may be important for activation of tyrosine kinases, some of which could be involved in cancer progression. Therefore, modulation of the encoded protein could be useful as a therapeutic agent against cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014],
Product Name Alternative
SLC39A7; HKE4; RING5; Zinc transporter SLC39A7; Histidine-rich membrane protein Ke4; Really interesting new gene 5 protein; Solute carrier family 39 member 7
UniProt
Q92504
Swiss Prot
Q92504
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human SLC39A7. AA range:131-180
Target
ZIP7
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications.
Buffer
-20°C/1 year
Molecular Weight
50kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
50kD
Fragment
IgG
Subcellular Location
Endoplasmic reticulum membrane ; Multi-pass membrane protein . Golgi apparatus, cis-Golgi network membrane ; Multi-pass membrane protein .
Other Product Names
SLC39A7; HKE4; RING5; Zinc transporter SLC39A7; Histidine-rich membrane protein Ke4; Really interesting new gene 5 protein; Solute carrier family 39 member 7
Gene ID (Human)
7922

UniProtKB · Q92504

Zinc transporter SLC39A7

S39A7_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q92504
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
SLC39A7
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
B0UXF6, Q5STP8, Q9UIQ0
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Disease

Disease variant

Cellular component

Endoplasmic reticulumGolgi apparatusMembrane

Biological process

Ion transportTransportZinc transport

PTM

MethylationPhosphoprotein

Domain

TransmembraneTransmembrane helix

Ligand

Zinc

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