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UBR5 rabbit pAb

CAT: 0855-ES3670-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES3670-01Size:50 µL
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Background
This gene encodes a progestin-induced protein, which belongs to the HECT (homology to E6-AP carboxyl terminus) family. The HECT family proteins function as E3 ubiquitin-protein ligases, targeting specific proteins for ubiquitin-mediated proteolysis. This gene is localized to chromosome 8q22 which is disrupted in a variety of cancers. This gene potentially has a role in regulation of cell proliferation or differentiation. [provided by RefSeq, Jul 2008]
Description
This gene encodes a progestin-induced protein, which belongs to the HECT (homology to E6-AP carboxyl terminus) family. The HECT family proteins function as E3 ubiquitin-protein ligases, targeting specific proteins for ubiquitin-mediated proteolysis. This gene is localized to chromosome 8q22 which is disrupted in a variety of cancers. This gene potentially has a role in regulation of cell proliferation or differentiation. [provided by RefSeq, Jul 2008],
Product Name Alternative
UBR5; EDD; EDD1; HYD; KIAA0896; E3 ubiquitin-protein ligase UBR5; E3 ubiquitin-protein ligase; HECT domain-containing 1; Hyperplastic discs protein homolog; hHYD; Progestin-induced protein
UniProt
O95071
Swiss Prot
O95071
Reactivity
Human; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human EDD. AA range:1-50
Target
UBR5
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.
Buffer
-20°C/1 year
Molecular Weight
309kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
309kD
Fragment
IgG
Subcellular Location
Nucleus.
Other Product Names
UBR5; EDD; EDD1; HYD; KIAA0896; E3 ubiquitin-protein ligase UBR5; E3 ubiquitin-protein ligase; HECT domain-containing 1; Hyperplastic discs protein homolog; hHYD; Progestin-induced protein
Gene ID (Human)
51366

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