TGFα rabbit pAb

• Background :

  This gene encodes a growth factor that is a ligand for the epidermal growth factor receptor, which activates a signaling pathway for cell proliferation, differentiation and development. This protein may act as either a transmembrane-bound ligand or a soluble ligand. This gene has been associated with many types of cancers, and it may also be involved in some cases of cleft lip/palate. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]

• Description :

  This gene encodes a growth factor that is a ligand for the epidermal growth factor receptor, which activates a signaling pathway for cell proliferation, differentiation and development. This protein may act as either a transmembrane-bound ligand or a soluble ligand. This gene has been associated with many types of cancers, and it may also be involved in some cases of cleft lip/palate. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011],

• UniProt :

  P01135

• Swiss Prot :

  P01135

• Reactivity :

  Human; Mouse; Rat; Monkey

• Immunogen :

  The antiserum was produced against synthesized peptide derived from human TGF alpha. AA range:111-160

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; IHC; IF; ELISA

• Concentration :

  1 mg/ml

• Dilution :

  Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.

• Molecular Weight :

  10kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  10kD

• Fragment :

  IgG

• Subcellular Location :

  [Transforming growth factor alpha]: Secreted, extracellular space.; [Protransforming growth factor alpha]: Cell membrane; Single-pass type I membrane protein.

• Other Product Names :

  TGFA; Protransforming growth factor alpha

• Gene ID (Human) :

  7039