TGFβ RIII (phospho Thr842) rabbit pAb
CAT:
855-ES7380-01
Size:
50 μL
Price:
Ask
- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
TGFβ RIII (phospho Thr842) rabbit pAb
- Description: This locus encodes the transforming growth factor (TGF)-beta type III receptor. The encoded receptor is a membrane proteoglycan that often functions as a co-receptor with other TGF-beta receptor superfamily members. Ectodomain shedding produces soluble TGFBR3, which may inhibit TGFB signaling. Decreased expression of this receptor has been observed in various cancers. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Sep 2010],
- Synonyms: TGFBR3; Transforming growth factor beta receptor type 3; TGF-beta receptor type 3; TGFR-3; Betaglycan; Transforming growth factor beta receptor III; TGF-beta receptor type III
- Gene ID: 7049
- UniProt: Q03167
- Cellular Locus: Secreted. Secreted, extracellular space. Cell membrane ; Single-pass type I membrane protein. Exists both as a membrane-bound form and as soluble form in serum and in the extracellular matrix.
- Host: Rabbit
- Species Reactivity: Human, Mouse, Rat
- Immunogen: The antiserum was produced against synthesized peptide derived from human TGF beta Receptor III around the phosphorylation site of Thr842. AA range:801-850
- Clonality: Polyclonal
- Validated Applications: IHC, IF, ELISA
- Stability: 1 year
- Concentration: 1 mg/mL
- Dilution: Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.
- Storage Conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.