Products for Research Use Only
RegisterLogin

SH-PTP2 rabbit pAb

CAT: 0855-ES3441-01Size: 50 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0855-ES3441-01Size:50 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations in this gene are a cause of Noonan syndrome as well as acute myeloid leukemia. [provided by RefSeq, Aug 2016]
Description
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations in this gene are a cause of Noonan syndrome as well as acute myeloid leukemia. [provided by RefSeq, Aug 2016],
UniProt
Q06124
Swiss Prot
Q06124
Reactivity
Human; Mouse; Rat; Monkey
Immunogen
The antiserum was produced against synthesized peptide derived from human SH-PTP2. AA range:321-370
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Molecular Weight
68kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
68kD
Fragment
IgG
Subcellular Location
Cytoplasm . Nucleus .
Other Product Names
PTPN11; PTP2C; SHPTP2; Tyrosine-protein phosphatase non-receptor type 11; Protein-tyrosine phosphatase 1D; PTP-1D; Protein-tyrosine phosphatase 2C; PTP-2C; SH-PTP2; SHP-2; Shp2; SH-PTP3
Gene ID (Human)
5781

Related Products

CatalogName
ES1455-01SH-PTP2 (phospho Tyr542) rabbit pAb
ES1456-01SH-PTP2 (phospho Tyr580) rabbit pAb
ES6933-01SH-PTP1 rabbit pAb
ES3438-01SH-PTP1 rabbit pAb
ES6931-01SH-PTP1 (phospho Tyr564) rabbit pAb
ES6932-01SH-PTP1 (phospho Tyr536) rabbit pAb
ES10226-01PTPA rabbit pAb
ES5474-01PTP22 rabbit pAb
ES3281-01PTPζ rabbit pAb
ES6939-01PTPα rabbit pAb

Alternative Products

CatalogName
E60M0535SH-PTP2 Rabbit mAb
E28PT4294SH-PTP2 Rabbit Polyclonal Antibody
M3391-01SH-PTP2 (AB2059) Rabbit mAb
AMRe21267-01SH-PTP2 Rabbit Monoclonal Antibody
GTR18050901-01SH-PTP2 rabbit pAb Antibody
HY-P86320SH-PTP2 Antibody (YA6012, Rabbit)
E53P05848SH-PTP2 Tyr542 Rabbit Polyclonal Antibody
M00150-5-20μlAnti-SH-PTP2 Rabbit Monoclonal Antibody
E60M3834SH-PTP2 (Phospho Tyr542) Rabbit mAb
YM8403-01SH-PTP2 (PT0592R) PT® Rabbit mAb

Popular Products