Products for Research Use Only
RegisterLogin

RUNX3 rabbit pAb

CAT: 0855-ES3400-01Size: 50 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0855-ES3400-01Size:50 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]
Description
This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016],
Product Name Alternative
RUNX3; AML2; CBFA3; PEBP2A3; Runt-related transcription factor 3; Acute myeloid leukemia 2 protein; Core-binding factor subunit alpha-3; CBF-alpha-3; Oncogene AML-2; Polyomavirus enhancer-binding protein 2 alpha C subunit; PEA2-alpha C; PEB
UniProt
Q13761
Swiss Prot
Q13761
Reactivity
Human; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human RUNX3. AA range:133-182
Target
RUNX3
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
Buffer
-20°C/1 year
Molecular Weight
44kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
44kD
Fragment
IgG
Subcellular Location
Nucleus . Cytoplasm . The tyrosine phosphorylated form localizes to the cytoplasm. Translocates from the cytoplasm to the nucleus following TGF-beta stimulation. .
Other Product Names
RUNX3; AML2; CBFA3; PEBP2A3; Runt-related transcription factor 3; Acute myeloid leukemia 2 protein; Core-binding factor subunit alpha-3; CBF-alpha-3; Oncogene AML-2; Polyomavirus enhancer-binding protein 2 alpha C subunit; PEA2-alpha C; PEB
Gene ID (Human)
864

Related Products

CatalogName
ES7843-01RUNX3 Rabbit Polyclonal Antibody
ES7837-01RUNX1 rabbit pAb
ES4086-01RUNX2 rabbit pAb
ES7835-01RUNX1 (phospho Ser276) rabbit pAb
ES7833-01RUNX1 (phospho Ser249) rabbit pAb
ES20054-01RUNX1 (Acetyl Lys24) rabbit pAb
ES7834-01RUNX1 (phospho Ser435) rabbit pAb
ES4666-01RAB3IP rabbit pAb
ES20751-01Gab1 Rabbit rabbit pAb
ES20703-01JAK2 Rabbit rabbit pAb

Alternative Products

CatalogName
MBS8546720-01RUNX3 Rabbit pAb
MBS4764229-01RUNX3 Rabbit mAb
APRab17444-01RUNX3 Rabbit Polyclonal Antibody
AMRe87005-01RUNX3 Rabbit Monoclonal Antibody
APR27274N-01RUNX3 Rabbit pAb (APR27274N)
GTR18408067-01RUNX3 Recombinant Rabbit mAb
GB113627Anti-RUNX3 Rabbit pAb
SLM-60684R-01Rabbit Anti-RUNX3 antibody
HY-P81396-01RUNX3 Antibody (YA1141, Rabbit)
553216RUNX3

Popular Products