Rag C rabbit pAb

• Background:

  This gene encodes a member of the GTR/RAG GTP-binding protein family. The encoded protein is a monomeric guanine nucleotide-binding protein which forms a heterodimer with RRAGA and RRAGB and is primarily localized to the cytoplasm. The encoded protein promotes intracellular localization of the mTOR complex. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2012]

• Description:

  This gene encodes a member of the GTR/RAG GTP-binding protein family. The encoded protein is a monomeric guanine nucleotide-binding protein which forms a heterodimer with RRAGA and RRAGB and is primarily localized to the cytoplasm. The encoded protein promotes intracellular localization of the mTOR complex. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2012],

• Synonyms:

  RRAGC; Ras-related GTP-binding protein C; Rag C; RagC; GTPase-interacting protein 2; TIB929

• Gene ID:

  64121

• UniProt:

  Q9HB90

• Cellular Locus:

  Cytoplasm. Nucleus. Lysosome. Predominantly cytoplasmic. May shuttle between the cytoplasm and nucleus, depending on the bound nucleotide state of associated RRAGA (PubMed:11073942)..

• Host:

  Rabbit

• Species Reactivity:

  Human, Mouse, Rat

• Reactivity:

  Human; Mouse; Rat

• Immunogen:

  The antiserum was produced against synthesized peptide derived from human RRAGC. AA range:302-351

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Source:

  Rabbit

• Applications:

  WB, ELISA, IHC CoIP

• Validated Applications:

  WB, ELISA, IHC Co-IP

• Stability:

  -20°C/1 year

• Concentration:

  1 mg/mL

• Dilution:

  WB 1:500-2000; IHC-p 1:50-300; IP 1:50-200 ELISA 2000-20000

• Molecular Weight:

  44kD

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

• Observed Molecular Weight:

  44 kD

• Subcellular Location:

  Cytoplasm . Nucleus . Lysosome . Predominantly cytoplasmic. May shuttle between the cytoplasm and nucleus, depending on the bound nucleotide state of associated RRAGA (PubMed:11073942) . .

• Other Product Names:

  RRAGC; Ras-related GTP-binding protein C; Rag C; RagC; GTPase-interacting protein 2; TIB929

• Gene ID (Human):

  64121

• SwissProt (Human):

  Q9HB90