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Rabphilin-3A rabbit pAb

CAT: 0855-ES3298-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES3298-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Exocytosis of neurotransmitters and hormones is fundamental to synaptic neurotransmission and cell-cell communication. RAB3A (MIM 179390) is a small G protein that is thought to act at late stages of exocytosis, and RPH3A is a RAB3A effector (Lin et al., 2007 [PubMed 17149709]) .[supplied by OMIM, Jul 2008]
Description
Exocytosis of neurotransmitters and hormones is fundamental to synaptic neurotransmission and cell-cell communication. RAB3A (MIM 179390) is a small G protein that is thought to act at late stages of exocytosis, and RPH3A is a RAB3A effector (Lin et al. 2007 [PubMed 17149709]). [supplied by OMIM, Jul 2008],
Product Name Alternative
RPH3A; KIAA0985; Rabphilin-3A; Exophilin-1
UniProt
Q9Y2J0
Swiss Prot
Q9Y2J0
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human Rabphilin 3A. AA range:203-252
Target
Rabphilin 3A
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.
Buffer
-20°C/1 year
Molecular Weight
75kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
75kD
Fragment
IgG
Subcellular Location
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane . Cell projection, dendritic spine . Cell junction, synapse, postsynaptic cell membrane . Membrane ; Peripheral membrane protein .
Other Product Names
RPH3A; KIAA0985; Rabphilin-3A; Exophilin-1
Gene ID (Human)
22895

UniProtKB · Q9Y2J0

Rabphilin-3A

RP3A_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9Y2J0
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
RPH3A
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
B7Z3C3, Q96AE0
Protein keywords

Coding sequence diversity

Alternative splicing

Ligand

CalciumLipid-bindingMetal-bindingZinc

Cellular component

Cell membraneCell projectionCytoplasmic vesicleMembranePostsynaptic cell membraneSynapse

PTM

MethylationPhosphoproteinUbl conjugation

Biological process

Protein transportTransport

Technical term

Proteomics identificationReference proteome

Domain

RepeatZinc-finger

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