Rab 6C rabbit pAb

• Background:

  Function:Protein transport. Regulator of membrane traffic from the Golgi apparatus towards the endoplasmic reticulum (ER) . Has a low GTPase activity., PTM:Phosphorylated upon DNA damage, probably by ATM or ATR., similarity:Belongs to the small GTPase superfamily. Rab family., subunit:Interacts with SCYL1BP1. Interacts with VSP52 and RABGAP1. Isoform 1 interacts with RAB6KIFL but not isoform 2. Isoforms 1 and 2 interact with BICD1 and BICD2. Interacts with TMF1., tissue specificity:Ubiquitous.

• Description:

  Function: Protein transport. Regulator of membrane traffic from the Golgi apparatus towards the endoplasmic reticulum (ER). Has a low GTPase activity. PTM: Phosphorylated upon DNA damage, probably by ATM or ATR. similarity: Belongs to the small GTPase superfamily. Rab family. subunit: Interacts with SCYL1BP1. Interacts with VSP52 and RABGAP1. Isoform 1 interacts with RAB6KIFL but not isoform 2. Isoforms 1 and 2 interact with BICD1 and BICD2. Interacts with TMF1. tissue specificity: Ubiquitous.

• Synonyms:

  RAB6C; WTH3; Ras-related protein Rab-6C; Rab6-like protein WTH3

• Gene ID:

  84084

• UniProt:

  Q9H0N0

• Cellular Locus:

  Nucleus. Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.

• Host:

  Rabbit

• Species Reactivity:

  Human, Mouse, Rat

• Reactivity:

  Human; Mouse; Rat

• Immunogen:

  The antiserum was produced against synthesized peptide derived from human RAB6C. AA range:165-214

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Source:

  Rabbit

• Applications:

  WB, IHC

• Validated Applications:

  WB, IHC

• Stability:

  -20°C/1 year

• Concentration:

  1 mg/mL

• Dilution:

  WB 1:500-2000; IHC-p 1:50-300

• Molecular Weight:

  28kD

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

• Observed Molecular Weight:

  28 kD

• Subcellular Location:

  Nucleus . Cytoplasm . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome .

• Other Product Names:

  RAB6C; WTH3; Ras-related protein Rab-6C; Rab6-like protein WTH3

• Gene ID (Human):

  84084

• SwissProt (Human):

  Q9H0N0