PSMD12 rabbit pAb

CAT: 0855-ES3272-01Size: 50 µLDry Ice: NoHazardous: No
CAT#:0855-ES3272-01Size:50 µL
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Background
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. A pseudogene has been identified on chromosome 3. Alternatively spliced transcript variants encoding
Description
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. A pseudogene has been identified on chromosome 3. Alternatively spliced transcript variants encoding
UniProt
O00232
Swiss Prot
O00232
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human PSMD12. AA range:151-200
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Molecular Weight
50kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
50kD
Fragment
IgG
Subcellular Location
Proteasome complex, nucleoplasm, cytoplasm, cytosol, proteasome regulatory particle, proteasome regulatory particle, lid subcomplex, membrane, proteasome accessory complex, nuclear proteasome complex, extracellular exosome
Other Product Names
PSMD12; 26S proteasome non-ATPase regulatory subunit 12; 26S proteasome regulatory subunit RPN5; 26S proteasome regulatory subunit p55
Gene ID (Human)
5718

Related Products

CatalogName
ES3271-01PSMD11 rabbit pAb
ES13882-01PSMD1 rabbit pAb
ES3273-01PSMD2 rabbit pAb
ES6867-01PSMD3 rabbit pAb
ES19894-01PSMG1 rabbit pAb
ES13880-01PSMD8 rabbit pAb
ES13881-01PSMD5 rabbit pAb
ES13879-01PSME1 rabbit pAb
ES9289-01PSMD9 rabbit pAb
ES4666-01RAB3IP rabbit pAb

Alternative Products

CatalogName
E47R13775PSMD12 Rabbit pAb
MBS4509278-01Rabbit anti-PSMD12 Antibody
NBP2-94102-0.02mLRabbit Polyclonal PSMD12 Antibody
APRab16617-01PSMD12 Rabbit Polyclonal Antibody
E2614522PSMD12 (Center) Rabbit pAb
APR26772N-01PSMD12 Rabbit pAb (APR26772N)
PA15065-01Rabbit Anti-Human PSMD12 pAb
A303-829A-TRabbit anti-PSMD12 Antibody, Affinity Purified
CSB-CL018902HU1PSMD12

Popular Products