PRPF18 rabbit pAb

• Background:

  Pre-mRNA splicing occurs in 2 sequential transesterification steps. The protein encoded by this gene is found to be essential for the catalytic step II in pre-mRNA splicing process. It is found in the spliceosome, and contains seven WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to the yeast splicing factor Prp18. [provided by RefSeq, Jul 2008]

• Description:

  Pre-mRNA splicing occurs in 2 sequential transesterification steps. The protein encoded by this gene is found to be essential for the catalytic step II in pre-mRNA splicing process. It is found in the spliceosome, and contains seven WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to the yeast splicing factor Prp18. [provided by RefSeq, Jul 2008],

• Synonyms:

  PRPF18; HPRP18; Pre-mRNA-splicing factor 18; PRP18 homolog; hPRP18

• Gene ID:

  8559

• UniProt:

  Q99633

• Cellular Locus:

  Nucleus speckle. Colocalizes with spliceosomal snRNPs..

• Host:

  Rabbit

• Species Reactivity:

  Human, Mouse, Rat

• Reactivity:

  Human; Mouse; Rat

• Immunogen:

  The antiserum was produced against synthesized peptide derived from human PRPF18. AA range:182-231

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Source:

  Rabbit

• Applications:

  WB, ELISA, IHC

• Validated Applications:

  WB, ELISA, IHC

• Stability:

  -20°C/1 year

• Concentration:

  1 mg/mL

• Dilution:

  WB 1:500-2000; IHC-p 1:50-300; ELISA 2000-20000

• Molecular Weight:

  40kD

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

• Observed Molecular Weight:

  40 kD

• Subcellular Location:

  Nucleus speckle . Colocalizes with spliceosomal snRNPs. .

• Other Product Names:

  PRPF18; HPRP18; Pre-mRNA-splicing factor 18; PRP18 homolog; hPRP18

• Gene ID (Human):

  8559

• SwissProt (Human):

  Q99633