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PP2Cκ rabbit pAb

CAT: 0855-ES3249-02Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0855-ES3249-02Size:100 µL
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Background
This gene encodes a member of the PPM family of Mn2+/Mg2+-dependent protein phosphatases. The encoded protein, essential for cell survival and development, is targeted to the mitochondria where it plays a key role in regulation of the mitochondrial permeability transition pore. [provided by RefSeq, Sep 2012]
Description
This gene encodes a member of the PPM family of Mn2+/Mg2+-dependent protein phosphatases. The encoded protein, essential for cell survival and development, is targeted to the mitochondria where it plays a key role in regulation of the mitochondrial permeability transition pore. [provided by RefSeq, Sep 2012],
Product Name Alternative
PPM1K; PP2CM; Protein phosphatase 1K; mitochondrial; PP2C domain-containing protein phosphatase 1K; PP2C-like mitochondrial protein; PP2C-type mitochondrial phosphoprotein phosphatase; PTMP; Protein phosphatase 2C isoform kappa; PP2C-kappa
UniProt
Q8N3J5
Swiss Prot
Q8N3J5
Reactivity
Human; Rat; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human PPM1K. AA range:205-254
Target
PP2Cκ
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Buffer
-20°C/1 year
Molecular Weight
45kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
45kD
Fragment
IgG
Subcellular Location
Mitochondrion matrix .
Other Product Names
PPM1K; PP2CM; Protein phosphatase 1K; mitochondrial; PP2C domain-containing protein phosphatase 1K; PP2C-like mitochondrial protein; PP2C-type mitochondrial phosphoprotein phosphatase; PTMP; Protein phosphatase 2C isoform kappa; PP2C-kappa
Gene ID (Human)
152926

UniProtKB · Q8N3J5

Protein phosphatase Mn(2+)-dependent 1K

PPM1K_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q8N3J5
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
PPM1K
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
3.1.3.16
Processing
Precursor
Secondary accessions
B2RAZ1, Q05CT5, Q49AB5, Q4W5E6, Q56AN8, Q8IUZ7, Q8IXG7, Q8ND70, Q96NT4
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Molecular function

HydrolaseProtein phosphatase

Ligand

ManganeseMetal-binding

Cellular component

Mitochondrion

PTM

Phosphoprotein

Domain

Transit peptide