PDE4C rabbit pAb

• Background:

  The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE4 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011]

• Description:

  The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE4 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2011],

• UniProt:

  Q08493

• Swiss Prot:

  Q08493

• Reactivity:

  Human; Mouse; Rat

• Immunogen:

  The antiserum was produced against synthesized peptide derived from human PDE4C. AA range:291-340

• Clonality:

  Polyclonal

• Source:

  Rabbit

• Applications:

  WB; ELISA; IHC

• Concentration:

  1 mg/ml

• Dilution:

  WB 1:500-2000; IHC-p 1:50-300; ELISA 2000-20000

• Molecular Weight:

  80kD

• Storage Conditions:

  -20°C/1 year

• Observed Molecular Weight:

  80kD

• Fragment:

  IgG

• Subcellular Location:

  Cell projection, cilium .

• Other Product Names:

  PDE4C; DPDE1; cAMP-specific 3'; 5'-cyclic phosphodiesterase 4C; DPDE1; PDE21

• Gene ID (Human):

  5143