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Pax-2 rabbit pAb

CAT: 0855-ES3152-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES3152-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
PAX2 encodes paired box gene 2, one of many human homologues of the Drosophila melanogaster gene prd. The central feature of this transcription factor gene family is the conserved DNA-binding paired box domain. PAX2 is believed to be a target of transcriptional supression by the tumor suppressor gene WT1. Mutations within PAX2 have been shown to result in optic nerve colobomas and renal hypoplasia. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Dec 2014]
Description
PAX2 encodes paired box gene 2, one of many human homologues of the Drosophila melanogaster gene prd. The central feature of this transcription factor gene family is the conserved DNA-binding paired box domain. PAX2 is believed to be a target of transcriptional supression by the tumor suppressor gene WT1. Mutations within PAX2 have been shown to result in optic nerve colobomas and renal hypoplasia. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Dec 2014],
UniProt
Q02962
Swiss Prot
Q02962
Reactivity
Human; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human Pax-2. AA range:144-193
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.
Molecular Weight
42,35kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
42,35kD
Fragment
IgG
Subcellular Location
Nucleus.
Other Product Names
PAX2; Paired box protein Pax-2
Gene ID (Human)
5076

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