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P120 rabbit pAb

CAT: 0855-ES3092-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES3092-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Catenin delta 1 (CTNND1) Homo sapiens This gene encodes a member of the Armadillo protein family, which function in adhesion between cells and signal transduction. Multiple translation initiation codons and alternative splicing result in many different isoforms being translated. Not all of the full-length natures of the described transcript variants have been determined. Read-through transcription also exists between this gene and the neighboring upstream thioredoxin-related transmembrane protein 2 (TMX2) gene. [provided by RefSeq, Dec 2010]
Description
Catenin delta 1 (CTNND1) Homo sapiens This gene encodes a member of the Armadillo protein family, which function in adhesion between cells and signal transduction. Multiple translation initiation codons and alternative splicing result in many different isoforms being translated. Not all of the full-length natures of the described transcript variants have been determined. Read-through transcription also exists between this gene and the neighboring upstream thioredoxin-related transmembrane protein 2 (TMX2) gene. [provided by RefSeq, Dec 2010],
UniProt
O60716
Swiss Prot
O60716
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human Catenin-delta1. AA range:201-250
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Molecular Weight
108kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
108kD
Fragment
IgG
Subcellular Location
Cell junction, adherens junction . Cytoplasm . Nucleus . Cell membrane . Interaction with GLIS2 promotes nuclear translocation (By similarity) . Detected at cell-cell contacts (PubMed:15240885, PubMed:17047063) . NANOS1 induces its translocation from sites of cell-cell contact to the cytoplasm (PubMed:17047063) . CDH1 enhances cell membrane localization (PubMed:15240885) . Isoforms 4A and 1AB are excluded from the nucleus (PubMed:11896187) . .; [Isoform 1A]: Nucleus .; [Isoform 2A]: Nucleus .; [Isoform 3A]: Nucleus .
Other Product Names
CTNND1; KIAA0384; Catenin delta-1; Cadherin-associated Src substrate; CAS; p120 catenin; p120 (ctn) ; p120 (cas)
Gene ID (Human)
1500

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