Products for Research Use Only
RegisterLogin

Nanog P8 rabbit pAb

CAT: 0855-ES2895-01Size: 50 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0855-ES2895-01Size:50 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
This locus is a processed pseudogene of the transcription factor NANOG. NANOG plays a central role in regulating self-renewal in pluripotent stem cells and tumor cells. This pseudogene contains an intact open reading frame that could potentially encode a protein similar to NANOG. Although there is no evidence of transcription from this pseudogene, RT-PCR studies suggest that NANOGP8 may be expressed in some cancer cell lines. In vitro studies using a recombinant NANOGP8 protein have shown that the protein localizes to the nucleus and can promote cell proliferation, similar to NANOG. [provided by RefSeq, Sep 2009]
Description
This locus is a processed pseudogene of the transcription factor NANOG. NANOG plays a central role in regulating self-renewal in pluripotent stem cells and tumor cells. This pseudogene contains an intact open reading frame that could potentially encode a protein similar to NANOG. Although there is no evidence of transcription from this pseudogene, RT-PCR studies suggest that NANOGP8 may be expressed in some cancer cell lines. In vitro studies using a recombinant NANOGP8 protein have shown that the protein localizes to the nucleus and can promote cell proliferation, similar to NANOG. [provided by RefSeq, Sep 2009],
UniProt
Q6NSW7
Swiss Prot
Q6NSW7
Reactivity
Human; Rat; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human NANOGP8. AA range:51-100
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IF; ELISA; IHC
Concentration
1 mg/ml
Dilution
WB 1:500-2000; IF/ICC 1:50-200; ELISA 1:2000-20000; IHC-p 1:50-200
Molecular Weight
35kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
35kD
Fragment
IgG
Subcellular Location
Nucleus .
Other Product Names
NANOGP8; Putative homeobox protein NANOGP8
Gene ID (Human)
388112

UniProtKB · Q6NSW7

Homeobox protein NANOGP8

NANP8_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q6NSW7
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
NANOGP8
Protein existence
2: Evidence at transcript level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
J7H3Y9, J7H3Z5, J7H408, J7H412, J7H416, J7H738, J7H745, J7H749, J7H9S6, J7H9T4, J7HAW9, J7HAX1, J7HAX8
Protein keywords

Molecular function

DNA-binding

Domain

HomeoboxRepeat

Cellular component

Nucleus

Technical term

Reference proteome

Biological process

TranscriptionTranscription regulation

Related Products

CatalogName
ELK7557-01Mouse NANOG (NANOG Homeobox Protein) ELISA Kit
ES11270-01NANO2 rabbit pAb
ES8506-01Nanos Homologue 1 (NANOS1) rabbit pAb
ES4666-01RAB3IP rabbit pAb
ES20751-01Gab1 Rabbit rabbit pAb
ES20703-01JAK2 Rabbit rabbit pAb
ES20758-01ERK1 Rabbit rabbit pAb
ES20830-01ATG14L Rabbit rabbit pAb
ES20829-01ATG4a Rabbit rabbit pAb
ES20658-01NM23A Rabbit rabbit pAb

Alternative Products

CatalogName
MBS8545207-01NANOG Rabbit pAb
MBS9147809-01Nanog Rabbit mAb
GTR18220266-01Rabbit Nanog Antibody
249124NANOG (Nanog Homeobox)

Popular Products