MyD88 rabbit pAb
CAT:
855-ES2871-02
Size:
100 μL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
MyD88 rabbit pAb
- Description: This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010],
- Synonyms: MYD88; Myeloid differentiation primary response protein MyD88
- Gene ID: 4615
- UniProt: Q99836
- Cellular Locus: Cytoplasm. Nucleus.
- Host: Rabbit
- Species Reactivity: Human, Mouse, Rat, Pig
- Immunogen: The antiserum was produced against synthesized peptide derived from human MyD88. AA range:171-220
- Clonality: Polyclonal
- Validated Applications: IF, WB, IHC, ELISA
- Stability: 1 year
- Concentration: 1 mg/mL
- Dilution: IF: 1:50-200 Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunocytochemistry: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
- Molecular Weight: 33kD
- Storage Conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.