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MRP-L44 rabbit pAb

CAT: 0855-ES2841-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES2841-01Size:50 µL
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Background
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. [provided by RefSeq, Jul 2008]
Description
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. [provided by RefSeq, Jul 2008],
Product Name Alternative
MRPL44; 39S ribosomal protein L44; mitochondrial; L44mt; MRP-L44
UniProt
Q9H9J2
Swiss Prot
Q9H9J2
Reactivity
Human; Mouse; Rat; Monkey
Immunogen
The antiserum was produced against synthesized peptide derived from human MRPL44. AA range:221-270
Target
MRP-L44
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.
Buffer
-20°C/1 year
Molecular Weight
36kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
36kD
Fragment
IgG
Subcellular Location
Mitochondrion .
Other Product Names
MRPL44; 39S ribosomal protein L44; mitochondrial; L44mt; MRP-L44
Gene ID (Human)
65080

UniProtKB · Q9H9J2

Large ribosomal subunit protein mL44

RM44_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9H9J2
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
MRPL44
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
Q53S16, Q6IA62, Q9H821
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Disease

Disease variantPrimary mitochondrial disease

Cellular component

Mitochondrion

Molecular function

RibonucleoproteinRibosomal proteinRNA-binding

Domain

Transit peptide

Biological process

Translation regulation

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