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MEL-1B-R rabbit pAb

CAT: 0855-ES2776-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES2776-01Size:50 µL
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Background
This gene encodes one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. This gene product is an integral membrane protein that is a G-protein coupled, 7-transmembrane receptor. It is found primarily in the retina and brain although this detection requires RT-PCR. It is thought to participate in light-dependent functions in the retina and may be involved in the neurobiological effects of melatonin. [provided by RefSeq, Jul 2008]
Description
This gene encodes one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. This gene product is an integral membrane protein that is a G-protein coupled, 7-transmembrane receptor. It is found primarily in the retina and brain although this detection requires RT-PCR. It is thought to participate in light-dependent functions in the retina and may be involved in the neurobiological effects of melatonin. [provided by RefSeq, Jul 2008],
UniProt
P49286
Swiss Prot
P49286
Reactivity
Human; Rat; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human MTR1B. AA range:301-350
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC
Concentration
1 mg/ml
Dilution
WB 1:500-2000; IHC-p 1:50-300
Molecular Weight
40kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
40kD
Fragment
IgG
Subcellular Location
Cell membrane; Multi-pass membrane protein.
Other Product Names
MTNR1B; Melatonin receptor type 1B; Mel-1B-R; Mel1b receptor
Gene ID (Human)
4544

UniProtKB · P49286

Melatonin receptor type 1B

MTR1B_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P49286
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
MTNR1B
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
Mel-1B-R, Mel1b receptor
EC number
—
Processing
—
Secondary accessions
—
Protein keywords

Technical term

3D-structureReference proteome

Cellular component

Cell membraneMembrane

PTM

Disulfide bondGlycoprotein

Molecular function

G protein-coupled receptorReceptorTransducer

Domain

TransmembraneTransmembrane helix