Maspin rabbit pAb

• Background:

  Function:Tumor suppressor. It blocks the growth, invasion, and metastatic properties of mammary tumors. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity., similarity:Belongs to the serpin family. Ov-serpin subfamily., tissue specificity:Normal mammary epithelial cells.

• Description:

  Function: Tumor suppressor. It blocks the growth, invasion, and metastatic properties of mammary tumors. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity. similarity: Belongs to the serpin family. Ov-serpin subfamily. tissue specificity: Normal mammary epithelial cells.

• UniProt:

  P36952

• Swiss Prot:

  P36952

• Reactivity:

  Human; Mouse; Rat

• Immunogen:

  The antiserum was produced against synthesized peptide derived from human Serpin B5. AA range:91-140

• Clonality:

  Polyclonal

• Source:

  Rabbit

• Applications:

  WB; IHC; IF; ELISA

• Concentration:

  1 mg/ml

• Dilution:

  Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.

• Molecular Weight:

  40kD

• Storage Conditions:

  -20°C/1 year

• Observed Molecular Weight:

  40kD

• Fragment:

  IgG

• Subcellular Location:

  Secreted, extracellular space.

• Other Product Names:

  SERPINB5; PI5; Serpin B5; Maspin; Peptidase inhibitor 5; PI-5

• Gene ID (Human):

  5268