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LPD lipase rabbit pAb

CAT: 0855-ES2723-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES2723-01Size:50 µL
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Background
The protein encoded by this gene is a phospholipase that hydrolyzes phosphatidic acid to produce lysophosphatidic acid. Defects in this gene are a cause of susceptibility to familial hypertrigliceridemia. This gene is also expressed at high levels in Ewing family tumor cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]
Description
The protein encoded by this gene is a phospholipase that hydrolyzes phosphatidic acid to produce lysophosphatidic acid. Defects in this gene are a cause of susceptibility to familial hypertrigliceridemia. This gene is also expressed at high levels in Ewing family tumor cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014],
UniProt
Q6XZB0
Swiss Prot
Q6XZB0
Reactivity
Human; Rat; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human LIPI. AA range:289-338
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Molecular Weight
53kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
53kD
Fragment
IgG
Subcellular Location
[Isoform 1]: Cell membrane . Secreted . May associate with lipid draft. .; [Isoform 2]: Cell membrane . Secreted . May associate with lipid draft. .
Other Product Names
LIPI; LPDL; PRED5; Lipase member I; LIPI; Cancer/testis antigen 17; CT17; LPD lipase; Membrane-associated phosphatidic acid-selective phospholipase A1-beta; mPA-PLA1 beta
Gene ID (Human)
149998

UniProtKB · Q6XZB0

Lipase member I

LIPI_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q6XZB0
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
LIPI
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
LIPI
EC number
3.1.1.-
Processing
Precursor
Secondary accessions
G1JSG3, G1JSG4, G1JSG5, G1JSG6, G1JSG7, G1JSG8, G1JSG9
Protein keywords

Coding sequence diversity

Alternative splicing

Cellular component

Cell membraneMembraneSecreted

PTM

Disulfide bondGlycoprotein

Molecular function

Heparin-bindingHydrolase

Biological process

Lipid degradationLipid metabolism

Technical term

Proteomics identificationReference proteome

Domain

Signal

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