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IQGAP1 rabbit pAb

CAT: 0855-ES2639-01Size: 50 µLDry Ice: NoHazardous: No
CAT#: ES2639-01Size: 50 µL
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AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
IQ motif containing GTPase activating protein 1 (IQGAP1) Homo sapiens This gene encodes a member of the IQGAP family. The protein contains four IQ domains, one calponin homology domain, one Ras-GAP domain and one WW domain. It interacts with components of the cytoskeleton, with cell adhesion molecules, and with several signaling molecules to regulate cell morphology and motility. Expression of the protein is upregulated by gene amplification in two gastric cancer cell lines. [provided by RefSeq, Jul 2008]
Description
IQ motif containing GTPase activating protein 1 (IQGAP1) Homo sapiens This gene encodes a member of the IQGAP family. The protein contains four IQ domains, one calponin homology domain, one Ras-GAP domain and one WW domain. It interacts with components of the cytoskeleton, with cell adhesion molecules, and with several signaling molecules to regulate cell morphology and motility. Expression of the protein is upregulated by gene amplification in two gastric cancer cell lines. [provided by RefSeq, Jul 2008],
Product Name Alternative
IQGAP1; KIAA0051; Ras GTPase-activating-like protein IQGAP1; p195
UniProt
P46940
Swiss Prot
P46940
Reactivity
Human; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human IQGAP1. AA range:247-296
Target
IQGAP1
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC
Concentration
1 mg/ml
Dilution
WB 1:500-2000; IHC-p 1:50-300
Buffer
-20°C/1 year
Molecular Weight
190kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
190kD
Fragment
IgG
Subcellular Location
Cell membrane . Nucleus . Cytoplasm . Subcellular distribution is regulated by the cell cycle, nuclear levels increase at G1/S phase (PubMed:20883816) . .
Other Product Names
IQGAP1; KIAA0051; Ras GTPase-activating-like protein IQGAP1; p195
Gene ID (Human)
8826

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