IQGAP1 rabbit pAb

• Background :

  IQ motif containing GTPase activating protein 1 (IQGAP1) Homo sapiens This gene encodes a member of the IQGAP family. The protein contains four IQ domains, one calponin homology domain, one Ras-GAP domain and one WW domain. It interacts with components of the cytoskeleton, with cell adhesion molecules, and with several signaling molecules to regulate cell morphology and motility. Expression of the protein is upregulated by gene amplification in two gastric cancer cell lines. [provided by RefSeq, Jul 2008]

• Description :

  IQ motif containing GTPase activating protein 1 (IQGAP1) Homo sapiens This gene encodes a member of the IQGAP family. The protein contains four IQ domains, one calponin homology domain, one Ras-GAP domain and one WW domain. It interacts with components of the cytoskeleton, with cell adhesion molecules, and with several signaling molecules to regulate cell morphology and motility. Expression of the protein is upregulated by gene amplification in two gastric cancer cell lines. [provided by RefSeq, Jul 2008],

• UniProt :

  P46940

• Swiss Prot :

  P46940

• Reactivity :

  Human; Mouse

• Immunogen :

  The antiserum was produced against synthesized peptide derived from human IQGAP1. AA range:247-296

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; IHC

• Concentration :

  1 mg/ml

• Dilution :

  WB 1:500-2000; IHC-p 1:50-300

• Molecular Weight :

  190kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  190kD

• Fragment :

  IgG

• Subcellular Location :

  Cell membrane . Nucleus . Cytoplasm . Subcellular distribution is regulated by the cell cycle, nuclear levels increase at G1/S phase (PubMed:20883816) . .

• Other Product Names :

  IQGAP1; KIAA0051; Ras GTPase-activating-like protein IQGAP1; p195

• Gene ID (Human) :

  8826