IKKα/β rabbit pAb

• Background:

  This gene encodes a member of the serine/threonine protein kinase family. The encoded protein, a component of a cytokine-activated protein complex that is an inhibitor of the essential transcription factor NF-kappa-B complex, phosphorylates sites that trigger the degradation of the inhibitor via the ubiquination pathway, thereby activating the transcription factor. [provided by RefSeq, Jul 2008]

• Description:

  This gene encodes a member of the serine/threonine protein kinase family. The encoded protein, a component of a cytokine-activated protein complex that is an inhibitor of the essential transcription factor NF-kappa-B complex, phosphorylates sites that trigger the degradation of the inhibitor via the ubiquination pathway, thereby activating the transcription factor. [provided by RefSeq, Jul 2008],

• UniProt:

  O15111/O14920

• Swiss Prot:

  O15111/O14920

• Reactivity:

  Human; Mouse; Rat; Pig

• Immunogen:

  The antiserum was produced against synthesized peptide derived from human IKK-alpha/beta. AA range:141-190

• Clonality:

  Polyclonal

• Source:

  Rabbit

• Applications:

  WB; IHC; IF; ELISA

• Concentration:

  1 mg/ml

• Dilution:

  Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.

• Molecular Weight:

  85kD

• Storage Conditions:

  -20°C/1 year

• Observed Molecular Weight:

  85kD

• Fragment:

  IgG

• Subcellular Location:

  Cytoplasm . Nucleus . Shuttles between the cytoplasm and the nucleus.

• Other Product Names:

  CHUK; IKKA; TCF16; Inhibitor of nuclear factor kappa-B kinase subunit alpha; I-kappa-B kinase alpha; IKK-A; IKK-alpha; IkBKA; IkappaB kinase; Conserved helix-loop-helix ubiquitous kinase; I-kappa-B kinase 1; IKK1; Nuclear factor NF-kappa-B

• Gene ID (Human):

  1147/3551