Products for Research Use Only
RegisterLogin

IKKα (phospho Thr23) rabbit pAb

CAT: 0855-ES1336-01Size: 50 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0855-ES1336-01Size:50 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
This gene encodes a member of the serine/threonine protein kinase family. The encoded protein, a component of a cytokine-activated protein complex that is an inhibitor of the essential transcription factor NF-kappa-B complex, phosphorylates sites that trigger the degradation of the inhibitor via the ubiquination pathway, thereby activating the transcription factor. [provided by RefSeq, Jul 2008]
Description
This gene encodes a member of the serine/threonine protein kinase family. The encoded protein, a component of a cytokine-activated protein complex that is an inhibitor of the essential transcription factor NF-kappa-B complex, phosphorylates sites that trigger the degradation of the inhibitor via the ubiquination pathway, thereby activating the transcription factor. [provided by RefSeq, Jul 2008],
UniProt
O15111
Swiss Prot
O15111
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human IKK-alpha around the phosphorylation site of Thr23. AA range:15-64
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.
Storage Conditions
-20°C/1 year
Fragment
IgG
Subcellular Location
Cytoplasm . Nucleus . Shuttles between the cytoplasm and the nucleus.
Other Product Names
CHUK; IKKA; TCF16; Inhibitor of nuclear factor kappa-B kinase subunit alpha; I-kappa-B kinase alpha; IKK-A; IKK-alpha; IkBKA; IkappaB kinase; Conserved helix-loop-helix ubiquitous kinase; I-kappa-B kinase 1; IKK1; Nuclear factor NF-kappa-B
Gene ID (Human)
1147

UniProtKB · O15111

Inhibitor of nuclear factor kappa-B kinase subunit alpha

IKKA_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
O15111
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
CHUK
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
I-kappa-B kinase alpha, IKK-A, IKK-alpha, IkBKA, IkappaB kinase
EC number
2.7.11.10
Processing
—
Secondary accessions
O14666, Q13132, Q5W0I4, Q92467
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

AcetylationPhosphoproteinUbl conjugation

Ligand

ATP-bindingNucleotide-binding

Cellular component

CytoplasmNucleus

Molecular function

KinaseSerine/threonine-protein kinaseTransferase

Related Products

CatalogName
ES15493-01IKKε (phospho-Ser172) rabbit pAb
ES7803-01IKKγ (phospho Ser376) rabbit pAb
ES5865-01IKKβ (phospho Tyr188) rabbit pAb
ES7801-01IKKγ (phospho Ser85) rabbit pAb
ES5866-01IKKβ (phospho Tyr199) rabbit pAb
ES7802-01IKKγ (phospho Ser31) rabbit pAb
ES1337-01IKKα/β (phospho Ser180/181) rabbit pAb
ES4646-01IKKα/β (phospho Ser176/177) rabbit pAb
ES2601-01IKKα/β rabbit pAb
ES5867-01IKKβ rabbit pAb

Alternative Products

CatalogName
320095IKK a (Phospho-Thr23)
A7117-01IKKα (phospho Thr23) Antibody
11129-01IKK α (Phospho-Thr23) Antibody
ABM0224IKK a (Phospho-Thr23) Antibody
E11-7117AIKKα (Phospho- Thr23) Antibody
79-161IKK a (phospho Thr23) Antibody
GTR18191054-01IKK-α (Phospho-Thr23) Antibody
GTR18086214Anti-IKKß (Phospho-Thr23)
E47R3229Phospho-IKK alpha (Thr23) Rabbit pAb
E28PP0140IKKα (phospho Thr23) Rabbit Polyclonal Antibody

Popular Products