HDAC6 rabbit pAb

CAT: 0855-ES2504-01Size: 50 µLDry Ice: NoHazardous: No
CAT#:0855-ES2504-01Size:50 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It contains an internal duplication of two catalytic domains which appear to function independently of each other. This protein possesses histone deacetylase activity and represses transcription. [provided by RefSeq, Jul 2008]
Description
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It contains an internal duplication of two catalytic domains which appear to function independently of each other. This protein possesses histone deacetylase activity and represses transcription. [provided by RefSeq, Jul 2008],
Product Name Alternative
HDAC6; KIAA0901; JM21; Histone deacetylase 6; HD6
UniProt
Q9UBN7
Swiss Prot
Q9UBN7
Reactivity
Human; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human HDAC6. AA range:7-56
Target
HDAC6
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Buffer
-20°C/1 year
Molecular Weight
131kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
131kD
Fragment
IgG
Subcellular Location
Cytoplasm . Cytoplasm, cytoskeleton . Nucleus . Perikaryon . Cell projection, dendrite . Cell projection, axon . It is mainly cytoplasmic, where it is associated with microtubules. .
Other Product Names
HDAC6; KIAA0901; JM21; Histone deacetylase 6; HD6
Gene ID (Human)
10013

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