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GCN5 rabbit pAb

CAT: 0855-ES2409-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES2409-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
KAT2A, or GCN5, is a histone acetyltransferase (HAT) that functions primarily as a transcriptional activator. It also functions as a repressor of NF-kappa-B (see MIM 164011) by promoting ubiquitination of the NF-kappa-B subunit RELA (MIM 164014) in a HAT-independent manner (Mao et al., 2009 [PubMed 19339690]) .[supplied by OMIM, Sep 2009]
Description
KAT2A, or GCN5, is a histone acetyltransferase (HAT) that functions primarily as a transcriptional activator. It also functions as a repressor of NF-kappa-B (see MIM 164011) by promoting ubiquitination of the NF-kappa-B subunit RELA (MIM 164014) in a HAT-independent manner (Mao et al. 2009 [PubMed 19339690]). [supplied by OMIM, Sep 2009],
UniProt
Q92830
Swiss Prot
Q92830
Reactivity
Human; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human GCN5L2. AA range:691-740
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Molecular Weight
100kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
100kD
Fragment
IgG
Subcellular Location
Nucleus . Chromosome . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Mainly localizes to the nucleus (PubMed:27796307) . Also localizes to centrosomes in late G1 and around the G1/S transition, coinciding with the onset of centriole formation (PubMed:27796307) . .
Other Product Names
KAT2A; GCN5; GCN5L2; HGCN5; Histone acetyltransferase KAT2A; General control of amino acid synthesis protein 5-like 2; Histone acetyltransferase GCN5; HsGCN5; Lysine acetyltransferase 2A; STAF97
Gene ID (Human)
2648

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