GBP3 rabbit pAb

• Background :

  This gene encodes a member of the guanylate-binding protein (GBP) family. GBPs specifically bind guanine nucleotides (GMP, GDP, and GTP) and contain two of the three consensus motifs found in typical GTP-binding proteins. The encoded protein interacts with a member of the germinal center kinase family. Multiple transcript variants encoding different isoforms have been been found for this gene. [provided by RefSeq, Jan 2016]

• Description :

  This gene encodes a member of the guanylate-binding protein (GBP) family. GBPs specifically bind guanine nucleotides (GMP, GDP, and GTP) and contain two of the three consensus motifs found in typical GTP-binding proteins. The encoded protein interacts with a member of the germinal center kinase family. Multiple transcript variants encoding different isoforms have been been found for this gene. [provided by RefSeq, Jan 2016],

• UniProt :

  Q9H0R5

• Swiss Prot :

  Q9H0R5

• Reactivity :

  Human; Rat; Mouse

• Immunogen :

  The antiserum was produced against synthesized peptide derived from human GBP3. AA range:481-530

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; IHC; IF; ELISA

• Concentration :

  1 mg/ml

• Dilution :

  Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.

• Molecular Weight :

  64kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  64kD

• Fragment :

  IgG

• Subcellular Location :

  Cytoplasm . Cytoplasm, perinuclear region . Golgi apparatus membrane . Heterodimers with GBP1, GBP2 and GBP5 localize in the compartment of the prenylated GBPs: with GBP1 in a vesicle-like compartment, with GBP2, around the nucleus and with GBP-5, at the Golgi apparatus. .

• Other Product Names :

  GBP3; Guanylate-binding protein 3; GTP-binding protein 3; GBP-3; Guanine nucleotide-binding protein 3

• Gene ID (Human) :

  2635