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ERCC4 rabbit pAb

CAT: 0855-ES2292-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES2292-01Size:50 µL
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Background
The protein encoded by this gene forms a complex with ERCC1 and is involved in the 5' incision made during nucleotide excision repair. This complex is a structure specific DNA repair endonuclease that interacts with EME1. Defects in this gene are a cause of xeroderma pigmentosum complementation group F (XP-F), or xeroderma pigmentosum VI (XP6) .[provided by RefSeq, Mar 2009]
Description
The protein encoded by this gene forms a complex with ERCC1 and is involved in the 5' incision made during nucleotide excision repair. This complex is a structure specific DNA repair endonuclease that interacts with EME1. Defects in this gene are a cause of xeroderma pigmentosum complementation group F (XP-F), or xeroderma pigmentosum VI (XP6). [provided by RefSeq, Mar 2009],
Product Name Alternative
ERCC4; ERCC11; XPF; DNA repair endonuclease XPF; DNA excision repair protein ERCC-4; DNA repair protein complementing XP-F cells; Xeroderma pigmentosum group F-complementing protein
UniProt
Q92889
Swiss Prot
Q92889
Reactivity
Human; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human XPF. AA range:801-850
Target
ERCC4
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Buffer
-20°C/1 year
Molecular Weight
103kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
103kD
Fragment
IgG
Subcellular Location
Nucleus . Chromosome . Localizes to sites of DNA damage. .
Other Product Names
ERCC4; ERCC11; XPF; DNA repair endonuclease XPF; DNA excision repair protein ERCC-4; DNA repair protein complementing XP-F cells; Xeroderma pigmentosum group F-complementing protein
Gene ID (Human)
2072