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EOMES rabbit pAb

CAT: 0855-ES2266-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES2266-01Size:50 µL
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Background
This gene belongs to the TBR1 (T-box brain protein 1) sub-family of T-box genes that share the common DNA-binding T-box domain. The encoded protein is a transcription factor which is crucial for embryonic development of mesoderm and the central nervous system in vertebrates. The protein may also be necessary for the differentiation of effector CD8+ T cells which are involved in defense against viral infections. A similar gene disrupted in mice is shown to be essential during trophoblast development and gastrulation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013]
Description
This gene belongs to the TBR1 (T-box brain protein 1) sub-family of T-box genes that share the common DNA-binding T-box domain. The encoded protein is a transcription factor which is crucial for embryonic development of mesoderm and the central nervous system in vertebrates. The protein may also be necessary for the differentiation of effector CD8+ T cells which are involved in defense against viral infections. A similar gene disrupted in mice is shown to be essential during trophoblast development and gastrulation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013],
Product Name Alternative
EOMES; TBR2; Eomesodermin homolog; T-box brain protein 2; T-brain-2; TBR-2
UniProt
O95936
Swiss Prot
O95936
Reactivity
Human; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human EOMES. AA range:59-108
Target
EOMES
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Buffer
-20°C/1 year
Molecular Weight
73kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
73kD
Fragment
IgG
Subcellular Location
Nucleus .
Other Product Names
EOMES; TBR2; Eomesodermin homolog; T-box brain protein 2; T-brain-2; TBR-2
Gene ID (Human)
8320

UniProtKB · O95936

Eomesodermin homolog

EOMES_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
O95936
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
EOMES
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
B7Z4I2, B7ZA51, G3XAI5, Q8TAZ2, Q9UPM7
Protein keywords

Molecular function

ActivatorDevelopmental proteinDNA-binding

Biological process

Adaptive immunityDifferentiationGastrulationImmunityTranscriptionTranscription regulation

Coding sequence diversity

Alternative splicingChromosomal rearrangement

Cellular component

Nucleus

PTM

Phosphoprotein

Technical term

Proteomics identificationReference proteome

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