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ECP rabbit pAb

CAT: 0855-ES2221-02Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0855-ES2221-02Size:100 µL
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Background
The protein encoded by this gene belongs to the pancreatic ribonuclease family, a subset of the ribonuclease A superfamily. The protein exhibits antimicrobial activity against pathogenic bacteria [provided by RefSeq, Oct 2014]
Description
The protein encoded by this gene belongs to the pancreatic ribonuclease family, a subset of the ribonuclease A superfamily. The protein exhibits antimicrobial activity against pathogenic bacteria [provided by RefSeq, Oct 2014],
Product Name Alternative
RNASE3; ECP; RNS3; Eosinophil cationic protein; ECP; Ribonuclease 3; RNase 3
UniProt
P12724
Swiss Prot
P12724
Reactivity
Human; Rat; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human ECP. AA range:102-151
Target
ECP
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Buffer
-20°C/1 year
Molecular Weight
18kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
18kD
Fragment
IgG
Subcellular Location
Secreted. Located in the matrix of eosinophil large specific granule, which are released following activation by an immune stimulus.
Other Product Names
RNASE3; ECP; RNS3; Eosinophil cationic protein; ECP; Ribonuclease 3; RNase 3
Gene ID (Human)
6037

UniProtKB · P12724

Eosinophil cationic protein

ECP_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P12724
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
RNASE3
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
ECP
EC number
3.1.27.-
Processing
Precursor
Secondary accessions
Q4VBC1, Q8WTP7, Q8WZ62, Q9GZN9
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Molecular function

AntibioticAntimicrobialEndonucleaseHydrolaseNuclease

PTM

Disulfide bondGlycoproteinNitration

Cellular component

Secreted

Domain

Signal

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