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Dok-2 rabbit pAb

CAT: 0855-ES2191-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES2191-01Size:50 µL
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Background
Docking protein 2 (DOK2) Homo sapiens The protein encoded by this gene is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210 (bcr/abl), a chimeric protein whose presence is associated with CML. This encoded protein binds p120 (RasGAP) from CML cells. [provided by RefSeq, Jul 2008]
Description
Docking protein 2 (DOK2) Homo sapiens The protein encoded by this gene is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210 (bcr/abl), a chimeric protein whose presence is associated with CML. This encoded protein binds p120 (RasGAP) from CML cells. [provided by RefSeq, Jul 2008],
UniProt
O60496
Swiss Prot
O60496
Reactivity
Human; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human p56 Dok-2. AA range:266-315
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Molecular Weight
46kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
46kD
Fragment
IgG
Subcellular Location
Cytosol
Other Product Names
DOK2; Docking protein 2; Downstream of tyrosine kinase 2; p56 (dok-2)
Gene ID (Human)
9046

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