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Creatine Kinase M rabbit pAb

CAT: 0855-ES2043-01Size: 50 µLDry Ice: NoHazardous: No
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Background
The protein encoded by this gene is a cytoplasmic enzyme involved in energy homeostasis and is an important serum marker for myocardial infarction. The encoded protein reversibly catalyzes the transfer of phosphate between ATP and various phosphogens such as creatine phosphate. It acts as a homodimer in striated muscle as well as in other tissues, and as a heterodimer with a similar brain isozyme in heart. The encoded protein is a member of the ATP:guanido phosphotransferase protein family. [provided by RefSeq, Jul 2008]
Description
The protein encoded by this gene is a cytoplasmic enzyme involved in energy homeostasis and is an important serum marker for myocardial infarction. The encoded protein reversibly catalyzes the transfer of phosphate between ATP and various phosphogens such as creatine phosphate. It acts as a homodimer in striated muscle as well as in other tissues, and as a heterodimer with a similar brain isozyme in heart. The encoded protein is a member of the ATP: guanido phosphotransferase protein family. [provided by RefSeq, Jul 2008],
UniProt
P06732
Swiss Prot
P06732
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human M-CK. AA range:10-59
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.
Molecular Weight
43kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
43kD
Fragment
IgG
Subcellular Location
Cytoplasm.
Other Product Names
CKM; CKMM; Creatine kinase M-type; Creatine kinase M chain; M-CK
Gene ID (Human)
1158

UniProtKB · P06732

Creatine kinase M-type

KCRM_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P06732
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
CKM
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
2.7.3.2
Processing
—
Secondary accessions
Q96QL9
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Ligand

ATP-bindingNucleotide-binding

Cellular component

Cytoplasm

Molecular function

KinaseTransferase

PTM

Phosphoprotein

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