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CdcA3 rabbit pAb

CAT: 0855-ES1935-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES1935-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Domain:The KEN box is required for the association with the APC/C-Cdh1 complex., function:F-box-like protein which is required for entry into mitosis. Acts by participating to E3 ligase complexes that mediate the ubiquitination and degradation of WEE1 kinase at G2/M phase., pathway:Protein modification; protein ubiquitination., PTM:Phosphorylated upon DNA damage, probably by ATM or ATR., PTM:Ubiquitinated and degraded by the APC/C-Cdh1 complex., subunit:Interacts with SKP1A. Part of a SCF (SKP1-cullin-F-box) protein ligase complex.
Description
Domain: The KEN box is required for the association with the APC/C-Cdh1 complex. function: F-box-like protein which is required for entry into mitosis. Acts by participating to E3 ligase complexes that mediate the ubiquitination and degradation of WEE1 kinase at G2/M phase. pathway: Protein modification; protein ubiquitination. PTM: Phosphorylated upon DNA damage, probably by ATM or ATR. PTM: Ubiquitinated and degraded by the APC/C-Cdh1 complex. subunit: Interacts with SKP1A. Part of a SCF (SKP1-cullin-F-box) protein ligase complex.
UniProt
Q99618
Swiss Prot
Q99618
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human CDCA3. AA range:219-268
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.
Molecular Weight
28kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
28kD
Fragment
IgG
Subcellular Location
Cytoplasm, cytosol .
Other Product Names
CDCA3; C8; GRCC8; TOME1; Cell division cycle-associated protein 3; Gene-rich cluster protein C8; Trigger of mitotic entry protein 1; TOME-1
Gene ID (Human)
83461

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