CdcA3 rabbit pAb
CAT:
855-ES1935-01
Size:
50 μL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
CdcA3 rabbit pAb
- Description: Domain: The KEN box is required for the association with the APC/C-Cdh1 complex. function: F-box-like protein which is required for entry into mitosis. Acts by participating to E3 ligase complexes that mediate the ubiquitination and degradation of WEE1 kinase at G2/M phase. pathway: Protein modification; protein ubiquitination. PTM: Phosphorylated upon DNA damage, probably by ATM or ATR. PTM: Ubiquitinated and degraded by the APC/C-Cdh1 complex. subunit: Interacts with SKP1A. Part of a SCF (SKP1-cullin-F-box) protein ligase complex.
- Synonyms: CDCA3; C8; GRCC8; TOME1; Cell division cycle-associated protein 3; Gene-rich cluster protein C8; Trigger of mitotic entry protein 1; TOME-1
- Gene ID: 83461
- UniProt: Q99618
- Cellular Locus: Cytoplasm, cytosol.
- Host: Rabbit
- Species Reactivity: Human, Mouse, Rat
- Immunogen: The antiserum was produced against synthesized peptide derived from human CDCA3. AA range:219-268
- Clonality: Polyclonal
- Validated Applications: WB, IHC, IF, ELISA
- Stability: 1 year
- Concentration: 1 mg/mL
- Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.
- Molecular Weight: 28kD
- Storage Conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.