CAR rabbit pAb

• Background:

  The protein encoded by this gene is a type I membrane receptor for group B coxsackieviruses and subgroup C adenoviruses. Several transcript variants encoding different isoforms have been found for this gene. Pseudogenes of this gene are found on chromosomes 15, 18, and 21. [provided by RefSeq, May 2011]

• Description:

  The protein encoded by this gene is a type I membrane receptor for group B coxsackieviruses and subgroup C adenoviruses. Several transcript variants encoding different isoforms have been found for this gene. Pseudogenes of this gene are found on chromosomes 15, 18, and 21. [provided by RefSeq, May 2011],

• UniProt:

  P78310

• Swiss Prot:

  P78310

• Reactivity:

  Human; Mouse; Rat

• Immunogen:

  The antiserum was produced against synthesized peptide derived from human CXADR. AA range:1-50

• Clonality:

  Polyclonal

• Source:

  Rabbit

• Applications:

  WB; ELISA

• Concentration:

  1 mg/ml

• Dilution:

  Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.

• Molecular Weight:

  40kD

• Storage Conditions:

  -20°C/1 year

• Observed Molecular Weight:

  40kD

• Fragment:

  IgG

• Subcellular Location:

  [Isoform 1]: Cell membrane ; Single-pass type I membrane protein . Basolateral cell membrane ; Single-pass type I membrane protein . Cell junction, tight junction . Cell junction, adherens junction . In epithelial cells localizes to the apical junction complex composed of tight and adherens junctions (PubMed:12297051) . In airway epithelial cells localized to basolateral membrane but not to apical surface (PubMed:11316797) . .; [Isoform 3]: Secreted .; [Isoform 4]: Secreted .; [Isoform 5]: Secreted .

• Other Product Names:

  CXADR; CAR; Coxsackievirus and adenovirus receptor; CAR; hCAR; CVB3-binding protein; Coxsackievirus B-adenovirus receptor; HCVADR

• Gene ID (Human):

  1525