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CARD 10 rabbit pAb

CAT: 0855-ES1839-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES1839-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The caspase recruitment domain (CARD) is a protein module that consists of 6 or 7 antiparallel alpha helices. It participates in apoptosis signaling through highly specific protein-protein homophilic interactions. Like several other CARD proteins, CARD10 belongs to the membrane-associated guanylate kinase (MAGUK) family and activates NF-kappa-B (NFKB; see MIM 164011) through BCL10 (MIM 603517) (Wang et al., 2001 [PubMed 11259443]) .[supplied by OMIM, Mar 2008]
Description
The caspase recruitment domain (CARD) is a protein module that consists of 6 or 7 antiparallel alpha helices. It participates in apoptosis signaling through highly specific protein-protein homophilic interactions. Like several other CARD proteins, CARD10 belongs to the membrane-associated guanylate kinase (MAGUK) family and activates NF-kappa-B (NFKB; see MIM 164011) through BCL10 (MIM 603517) (Wang et al. 2001 [PubMed 11259443]). [supplied by OMIM, Mar 2008],
Product Name Alternative
CARD10; CARMA3; Caspase recruitment domain-containing protein 10; CARD-containing MAGUK protein 3; Carma 3
UniProt
Q9BWT7
Swiss Prot
Q9BWT7
Reactivity
Human; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human CARD10. AA range:481-530
Target
CARD 10
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
Buffer
-20°C/1 year
Molecular Weight
120kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
120kD
Fragment
IgG
Subcellular Location
Cytoplasm .
Other Product Names
CARD10; CARMA3; Caspase recruitment domain-containing protein 10; CARD-containing MAGUK protein 3; Carma 3
Gene ID (Human)
29775