Calponin 2 rabbit pAb

• Background:

  The protein encoded by this gene, which can bind actin, calmodulin, troponin C, and tropomyosin, may function in the structural organization of actin filaments. The encoded protein could play a role in smooth muscle contraction and cell adhesion. Several pseudogenes of this gene have been identified, and are present on chromosomes 1, 2, 3, 6, 9, 11, 13, 15, 16, 21 and 22. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2015]

• Description:

  The protein encoded by this gene, which can bind actin, calmodulin, troponin C, and tropomyosin, may function in the structural organization of actin filaments. The encoded protein could play a role in smooth muscle contraction and cell adhesion. Several pseudogenes of this gene have been identified, and are present on chromosomes 1, 2, 3, 6, 9, 11, 13, 15, 16, 21 and 22. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2015],

• Synonyms:

  CNN2; Calponin-2; Calponin H2; smooth muscle; Neutral calponin

• Gene ID:

  1265

• UniProt:

  Q99439

• Cellular Locus:

  Stress fiber,cytoskeleton,cell-cell junction,cell-cell adherens junction,focal adhesion,membrane,extracellular exosome,

• Host:

  Rabbit

• Species Reactivity:

  Human, Mouse

• Reactivity:

  Human; Mouse

• Immunogen:

  The antiserum was produced against synthesized peptide derived from human CNN2. AA range:121-170

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Source:

  Rabbit

• Applications:

  WB, IF, ELISA

• Validated Applications:

  WB, IF, ELISA

• Stability:

  -20°C/1 year

• Concentration:

  1 mg/mL

• Dilution:

  Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.

• Molecular Weight:

  33kD

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

• Observed Molecular Weight:

  33 kD

• Subcellular Location:

  Stress fiber, cytoskeleton, cell-cell junction, cell-cell adherens junction, focal adhesion, membrane, extracellular exosome

• Other Product Names:

  CNN2; Calponin-2; Calponin H2; smooth muscle; Neutral calponin

• Gene ID (Human):

  1265

• SwissProt (Human):

  Q99439