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Calponin 2 rabbit pAb

CAT: 0855-ES1833-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES1833-01Size:50 µL
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Background
The protein encoded by this gene, which can bind actin, calmodulin, troponin C, and tropomyosin, may function in the structural organization of actin filaments. The encoded protein could play a role in smooth muscle contraction and cell adhesion. Several pseudogenes of this gene have been identified, and are present on chromosomes 1, 2, 3, 6, 9, 11, 13, 15, 16, 21 and 22. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2015]
Description
The protein encoded by this gene, which can bind actin, calmodulin, troponin C, and tropomyosin, may function in the structural organization of actin filaments. The encoded protein could play a role in smooth muscle contraction and cell adhesion. Several pseudogenes of this gene have been identified, and are present on chromosomes 1, 2, 3, 6, 9, 11, 13, 15, 16, 21 and 22. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2015],
Product Name Alternative
CNN2; Calponin-2; Calponin H2; smooth muscle; Neutral calponin
UniProt
Q99439
Swiss Prot
Q99439
Reactivity
Human; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human CNN2. AA range:121-170
Target
Calponin 2
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.
Buffer
-20°C/1 year
Molecular Weight
33kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
33kD
Fragment
IgG
Subcellular Location
Stress fiber, cytoskeleton, cell-cell junction, cell-cell adherens junction, focal adhesion, membrane, extracellular exosome
Other Product Names
CNN2; Calponin-2; Calponin H2; smooth muscle; Neutral calponin
Gene ID (Human)
1265

UniProtKB · Q99439

Calponin-2

CNN2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q99439
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
CNN2
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
A5D8U8, A6NFI4, D6W5X9, Q92578
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

AcetylationPhosphoprotein

Molecular function

Actin-bindingCalmodulin-binding

Coding sequence diversity

Alternative splicing

Domain

Repeat

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