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AR-β1 rabbit pAb

CAT: 0855-ES1712-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES1712-01Size:50 µL
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Background
The adrenergic receptors (subtypes alpha 1, alpha 2, beta 1, and beta 2) are a prototypic family of guanine nucleotide binding regulatory protein-coupled receptors that mediate the physiological effects of the hormone epinephrine and the neurotransmitter norepinephrine. Specific polymorphisms in this gene have been shown to affect the resting heart rate and can be involved in heart failure. [provided by RefSeq, Jul 2008]
Description
The adrenergic receptors (subtypes alpha 1, alpha 2, beta 1, and beta 2) are a prototypic family of guanine nucleotide binding regulatory protein-coupled receptors that mediate the physiological effects of the hormone epinephrine and the neurotransmitter norepinephrine. Specific polymorphisms in this gene have been shown to affect the resting heart rate and can be involved in heart failure. [provided by RefSeq, Jul 2008],
Product Name Alternative
ADRB1; ADRB1R; B1AR; Beta-1 adrenergic receptor; Beta-1 adrenoreceptor; Beta-1 adrenoceptor
UniProt
P08588
Swiss Prot
P08588
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human ADRB1. AA range:281-330
Target
AR-β1
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Buffer
-20°C/1 year
Molecular Weight
51kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
51kD
Fragment
IgG
Subcellular Location
Cell membrane ; Multi-pass membrane protein . Early endosome. Colocalizes with RAPGEF2 at the plasma membrane (By similarity) . Localized at the plasma membrane. Found in the Golgi upon GOPC overexpression. .
Other Product Names
ADRB1; ADRB1R; B1AR; Beta-1 adrenergic receptor; Beta-1 adrenoreceptor; Beta-1 adrenoceptor
Gene ID (Human)
153

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