AR-β1 rabbit pAb

• Background:

  The adrenergic receptors (subtypes alpha 1, alpha 2, beta 1, and beta 2) are a prototypic family of guanine nucleotide binding regulatory protein-coupled receptors that mediate the physiological effects of the hormone epinephrine and the neurotransmitter norepinephrine. Specific polymorphisms in this gene have been shown to affect the resting heart rate and can be involved in heart failure. [provided by RefSeq, Jul 2008]

• Description:

  The adrenergic receptors (subtypes alpha 1, alpha 2, beta 1, and beta 2) are a prototypic family of guanine nucleotide binding regulatory protein-coupled receptors that mediate the physiological effects of the hormone epinephrine and the neurotransmitter norepinephrine. Specific polymorphisms in this gene have been shown to affect the resting heart rate and can be involved in heart failure. [provided by RefSeq, Jul 2008],

• UniProt:

  P08588

• Swiss Prot:

  P08588

• Reactivity:

  Human; Mouse; Rat

• Immunogen:

  The antiserum was produced against synthesized peptide derived from human ADRB1. AA range:281-330

• Clonality:

  Polyclonal

• Source:

  Rabbit

• Applications:

  WB; IHC; IF; ELISA

• Concentration:

  1 mg/ml

• Dilution:

  Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.

• Molecular Weight:

  51kD

• Storage Conditions:

  -20°C/1 year

• Observed Molecular Weight:

  51kD

• Fragment:

  IgG

• Subcellular Location:

  Cell membrane ; Multi-pass membrane protein . Early endosome. Colocalizes with RAPGEF2 at the plasma membrane (By similarity) . Localized at the plasma membrane. Found in the Golgi upon GOPC overexpression. .

• Other Product Names:

  ADRB1; ADRB1R; B1AR; Beta-1 adrenergic receptor; Beta-1 adrenoreceptor; Beta-1 adrenoceptor

• Gene ID (Human):

  153