Products for Research Use Only
RegisterLogin

AMPKα1 rabbit pAb

CAT: 0855-ES1648-01Size: 50 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0855-ES1648-01Size:50 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK) . AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]
Description
The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008],
Product Name Alternative
PRKAA1; AMPK1; 5'-AMP-activated protein kinase catalytic subunit alpha-1; AMPK subunit alpha-1; Acetyl-CoA carboxylase kinase; ACACA kinase; Hydroxymethylglutaryl-CoA reductase kinase; HMGCR kinase; Tau-protein kinase PRKAA1
UniProt
Q13131
Swiss Prot
Q13131
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human AMPK1. AA range:451-500
Target
AMPKα1
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
Buffer
-20°C/1 year
Molecular Weight
65kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
65kD
Fragment
IgG
Subcellular Location
Cytoplasm . Nucleus . In response to stress, recruited by p53/TP53 to specific promoters. .
Other Product Names
PRKAA1; AMPK1; 5'-AMP-activated protein kinase catalytic subunit alpha-1; AMPK subunit alpha-1; Acetyl-CoA carboxylase kinase; ACACA kinase; Hydroxymethylglutaryl-CoA reductase kinase; HMGCR kinase; Tau-protein kinase PRKAA1
Gene ID (Human)
5562

Related Products

CatalogName
ES1649-01AMPKα1/2 rabbit pAb
ES1259-01AMPKβ1 (phospho Ser182) rabbit pAb
ES6735-01AMPKβ1 (phospho Ser182) rabbit pAb
ES6751-01AMPKγ1/2/3 rabbit pAb
ES6733-01AMPKα1 (phospho Ser496) rabbit pAb
ES18372-01AMPKα1 (phospho-Ser485) rabbit pAb
ES20225-01AMPKβ2 rabbit pAb
EA328-01AMPK α2 Rabbit pAb
EA231-01AMPKβ2 Rabbit pAb
ES6523-01AMPKγ2 rabbit pAb

Alternative Products

CatalogName
AF6195AMPKα1/AMPKα2 Rabbit Polyclonal Antibody
A28094-01AMPKα1 Rabbit mAb
A18855AMPKα1 Rabbit pAb
A22024-01AMPKγ1 Rabbit pAb
A4042AMPKβ1 Rabbit pAb
E60M0977AMPKβ1 Rabbit mAb
C06407-01AMPK α1 Rabbit mAb
C05602-01AMPK β1 Rabbit mAb

Popular Products