AMPKβ2 rabbit pAb

CAT: 0855-ES20225-01Size: 50 µLDry Ice: NoHazardous: No

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CAT#:0855-ES20225-01Size:50 µL

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Background

Function:AMPK is responsible for the regulation of fatty acid synthesis by phosphorylation of acetyl-CoA carboxylase. Also regulates cholesterol synthesis via phosphorylation and inactivation of hydroxymethylglutaryl-CoA reductase and hormone-sensitive lipase. This is a regulatory subunit, may be a positive regulator of AMPK activity. It may also serve as an adapter molecule for the catalytic alpha-subunit., PTM:Phosphorylated when associated with the catalytic subunit., similarity:Belongs to the 5'-AMP-activated protein kinase beta subunit family., subunit:Heterotrimer of an alpha catalytic subunit, a beta and a gamma non-catalytic regulatory subunits.

Description

Function: AMPK is responsible for the regulation of fatty acid synthesis by phosphorylation of acetyl-CoA carboxylase. Also regulates cholesterol synthesis via phosphorylation and inactivation of hydroxymethylglutaryl-CoA reductase and hormone-sensitive lipase. This is a regulatory subunit, may be a positive regulator of AMPK activity. It may also serve as an adapter molecule for the catalytic alpha-subunit. PTM: Phosphorylated when associated with the catalytic subunit. similarity: Belongs to the 5'-AMP-activated protein kinase beta subunit family. subunit: Heterotrimer of an alpha catalytic subunit, a beta and a gamma non-catalytic regulatory subunits.

UniProt

O43741

Swiss Prot

O43741

Reactivity

Human; Rat; Mouse

Immunogen

Synthesized peptide derived from human AMPKβ2 AA range: 130-210

Clonality

Polyclonal

Source

Rabbit

Applications

WB; ELISA

Concentration

1 mg/ml

Dilution

WB 1:1000-2000 ELISA 1:5000-20000

Storage Conditions

-20°C/1 year

Fragment

IgG

Other Product Names

5'-AMP-activated protein kinase subunit beta-2 (AMPK subunit beta-2)

Gene ID (Human)

5565

UniProtKB · O43741

5'-AMP-activated protein kinase subunit beta-2

AAKB2_HUMAN · Homo sapiens

View on UniProt ↗

Primary accession: O43741
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: PRKAB2
Protein existence: 1: Evidence at protein level
Organism: Homo sapiens (Human)
Taxonomy ID: 9606
Alternative names: AMPK subunit beta-2
EC number: —
Processing: —
Secondary accessions: A8K9V5, B4DH06, Q5VXY0

Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Biological process

Fatty acid biosynthesisFatty acid metabolismLipid biosynthesisLipid metabolism

PTM

Phosphoprotein

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