ABCC12 rabbit pAb

• Background:

  This gene is a member of the superfamily of ATP-binding cassette (ABC) transporters and the encoded protein contains two ATP-binding domains and 12 transmembrane regions. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies: ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White. This gene is a member of the MRP subfamily which is involved in multi-drug resistance. This gene and another subfamily member are arranged head-to-tail on chromosome 16q12.1. Increased expression of this gene is associated with breast cancer. [provided by RefSeq, Jul 2008]

• Description:

  This gene is a member of the superfamily of ATP-binding cassette (ABC) transporters and the encoded protein contains two ATP-binding domains and 12 transmembrane regions. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies: ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White. This gene is a member of the MRP subfamily which is involved in multi-drug resistance. This gene and another subfamily member are arranged head-to-tail on chromosome 16q12. 1. Increased expression of this gene is associated with breast cancer. [provided by RefSeq, Jul 2008],

• UniProt:

  Q96J65

• Swiss Prot:

  Q96J65

• Reactivity:

  Human; Rat; Mouse

• Immunogen:

  The antiserum was produced against synthesized peptide derived from human MRP9. AA range:691-740

• Clonality:

  Polyclonal

• Source:

  Rabbit

• Applications:

  WB; ELISA

• Concentration:

  1 mg/ml

• Dilution:

  Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.

• Molecular Weight:

  170kD

• Storage Conditions:

  -20°C/1 year

• Observed Molecular Weight:

  170kD

• Fragment:

  IgG

• Subcellular Location:

  Endoplasmic reticulum membrane ; Multi-pass membrane protein .

• Other Product Names:

  ABCC12; MRP9; Multidrug resistance-associated protein 9; ATP-binding cassette sub-family C member 12

• Gene ID (Human):

  94160