MLK3 (phospho Ser674) rabbit pAb
CAT:
855-ES1535-01
Size:
50 μL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
MLK3 (phospho Ser674) rabbit pAb
- Description: The protein encoded by this gene is a member of the serine/threonine kinase family. This kinase contains a SH3 domain and a leucine zipper-basic motif. This kinase preferentially activates MAPK8/JNK kinase, and functions as a positive regulator of JNK signaling pathway. This kinase can directly phosphorylate, and activates IkappaB kinase alpha and beta, and is found to be involved in the transcription activity of NF-kappaB mediated by Rho family GTPases and CDC42. [provided by RefSeq, Jul 2008],
- Synonyms: MAP3K11; MLK3; PTK1; SPRK; Mitogen-activated protein kinase kinase kinase 11; Mixed lineage kinase 3; Src-homology 3 domain-containing proline-rich kinase
- Gene ID: 4296
- UniProt: Q16584
- Cellular Locus: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Location is cell cycle dependent.
- Host: Rabbit
- Species Reactivity: Human, Mouse, Rat
- Immunogen: Synthesized phospho-peptide around the phosphorylation site of human MLK3 (phospho Ser674)
- Clonality: Polyclonal
- Validated Applications: WB, IHC
- Stability: 1 year
- Concentration: 1 mg/mL
- Dilution: WB 1:500-2000;IHC-p 1:50-300
- Storage Conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.