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Trimethyl chitosan

CAT: 0804-HY-148033-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-148033-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Trimethyl chitosan (N, N, N-Trimethylchitosan) is a multifunctional polymer and a derivative of Chitosan. Trimethyl chitosan targets the absorption enhancing proteins of tight junctions of intestinal and mucosal epithelial cells, induces tight junction protein rearrangement, and increases intercellular permeability. Trimethyl chitosan can stimulate the activity of promoting transmembrane transport of hydrophilic drugs (such as peptides and proteins) and can be used for drug delivery and synthesis of nanoparticles[1][2].
CAS Number
52349-26-5
Product Name Alternative
N, N, N-Trimethylchitosan
UNSPSC
12352211
Target
Drug Derivative
Type
Reference compound
Related Pathways
Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/trimethyl-chitosan.html
Solubility
H2O : 33.33 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
OC[C@@H]1[C@@H](C)[C@H](O)[C@@H]([N+](C)(C)C)[C@H](OC)O1.[Cl-].[n]
References & Citations
[1]Thanou MM, et al. Effect of degree of quaternization of N-trimethyl chitosan chloride for enhanced transport of hydrophilic compounds across intestinal caco-2 cell monolayers. J Control Release. 2000 Feb 14;64 (1-3) :15-25.|[2]Mourya VK, et al. Trimethyl chitosan and its applications in drug delivery. J Mater Sci Mater Med. 2009 May;20 (5) :1057-79.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported