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Cathepsin H rabbit pAb

CAT: 0855-ES1028-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES1028-01Size:50 µL
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Background
The protein encoded by this gene is a lysosomal cysteine proteinase important in the overall degradation of lysosomal proteins. It is composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. The encoded protein, which belongs to the peptidase C1 protein family, can act both as an aminopeptidase and as an endopeptidase. Increased expression of this gene has been correlated with malignant progression of prostate tumors. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2016]
Description
The protein encoded by this gene is a lysosomal cysteine proteinase important in the overall degradation of lysosomal proteins. It is composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. The encoded protein, which belongs to the peptidase C1 protein family, can act both as an aminopeptidase and as an endopeptidase. Increased expression of this gene has been correlated with malignant progression of prostate tumors. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2016],
UniProt
P09668
Swiss Prot
P09668
Reactivity
Human; Rat; Mouse
Immunogen
Synthesized peptide derived from Cathepsin H . at AA range: 70-150
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Molecular Weight
40kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
40kD
Fragment
IgG
Subcellular Location
Lysosome.
Other Product Names
CTSH; CPSB; Pro-cathepsin H
Gene ID (Human)
1512

UniProtKB · P09668

Pro-cathepsin H

CATH_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P09668
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
CTSH
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
B2RBK0, Q96NY6, Q9BUM7
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

Disulfide bondGlycoproteinZymogen

Molecular function

HydrolaseProteaseThiol protease

Cellular component

Lysosome

Domain

Signal

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