Vinculin Rabbit pAb

• Background:

  Vinculin is a membrane-cytoskeletal protein in focal adhesion plaques that is involved in linkage of integrin adhesion molecules to the actin cytoskeleton. Vinculin is a cytoskeletal protein associated with cell-cell and cell-matrix junctions, where it is thought to function as one of several interacting proteins involved in anchoring F-actin to the membrane.

• Description:

  Vinculin is a membrane-cytoskeletal protein in focal adhesion plaques that is involved in linkage of integrin adhesion molecules to the actin cytoskeleton. Vinculin is a cytoskeletal protein associated with cell-cell and cell-matrix junctions, where it is thought to function as one of several interacting proteins involved in anchoring F-actin to the membrane.

• Synonyms:

  CMD1W antibody, CMH15 antibody, metavinculin antibody, MVCL antibody, VINC antibody

• Gene ID:

  7414

• UniProt:

  P18206

• Cellular Locus:

  Cytoplasm,Cytoskeleton,Cell junction, Adherens junction

• Host:

  Rabbit

• Species Reactivity:

  Human, Rat, Mouse

• Reactivity:

  Human, Rat, Mouse

• Immunogen:

  Synthetic Peptide

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Source:

  Rabbit

• Applications:

  WB, IHC

• Validated Applications:

  WB, IHC

• Stability:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

• Concentration:

  1 mg/mL

• Dilution:

  WB 1:1,000-2,000 IHC 1:200-500

• Molecular Weight:

  130kDa

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

• Observed Molecular Weight:

  130 kDa

• Subcellular Location:

  Cytoplasm, Cytoskeleton, Cell junction, Adherens junction

• Other Product Names:

  CMD1W antibody, CMH15 antibody, metavinculin antibody, MVCL antibody, VINC antibody

• Gene ID (Human):

  7414

• SwissProt (Human):

  P18206