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AMPKα1 (9G3) Mouse mAb

CAT: 0855-EM1327-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-EM1327-01Size:50 µL
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Background
AMP-activated protein kinase (AMPK) is highly conserved from yeast to plants and animals and plays a key role in the regulation of energy homeostasis. AMPK is a heterotrimeric complex composed of a catalytic α subunit and regulatory β and γ subunits, each of which is encoded by two or three distinct genes (α1, 2; β1, 2; γ1, 2, 3) .
Description
AMP-activated protein kinase (AMPK) is highly conserved from yeast to plants and animals and plays a key role in the regulation of energy homeostasis. AMPK is a heterotrimeric complex composed of a catalytic α subunit and regulatory β and γ subunits, each of which is encoded by two or three distinct genes (α1, 2; β1, 2; γ1, 2, 3).
Product Name Alternative
AAPK1, 5 AMP activated protein kinase alpha 1 catalytic subunit, PRKAA1, SNF1A, MGC33776
UniProt
Q13131
Swiss Prot
Q13131
Reactivity
Human, Rat, Mouse
Immunogen
Recombinant Protein
Clonality
Monoclonal
Source
Mouse
Applications
WB, IHC
Concentration
1mg/mL
Dilution
WB 1:1,000-2,000 IHC 1:100-200
Buffer
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Molecular Weight
62kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
62kDa
Fragment
IgG1
Subcellular Location
Cytoplasm, Nucleus
Other Product Names
AAPK1, 5 AMP activated protein kinase alpha 1 catalytic subunit, PRKAA1, SNF1A, MGC33776
Gene ID (Human)
5562

UniProtKB · Q13131

5'-AMP-activated protein kinase catalytic subunit alpha-1

AAPK1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q13131
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
PRKAA1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
AMPK subunit alpha-1
EC number
2.7.11.1
Processing
—
Secondary accessions
A8MTQ6, B2R7E1, O00286, Q5D0E1, Q86VS1, Q9UNQ4
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Ligand

ATP-bindingMagnesiumMetal-bindingNucleotide-binding

Biological process

AutophagyBiological rhythmsCholesterol biosynthesisCholesterol metabolismFatty acid biosynthesisFatty acid metabolismHost-virus interactionLipid biosynthesisLipid metabolismSteroid biosynthesisSteroid metabolismSterol biosynthesisSterol metabolismTranscriptionTranscription regulationWnt signaling pathway

Molecular function

Chromatin regulatorKinaseSerine/threonine-protein kinaseTransferase

Cellular component

CytoplasmEndosomeNucleus

PTM

GlycoproteinPhosphoproteinUbl conjugation

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